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PD-1 Biosimilar Races Towards Approval: What This Means For Oncology

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Last week, the field of cancer immunotherapy reached a pretty exciting milestone with Allogene Therapeutics’ publication of Phase 1 results from their ALPHA/ALPHA2 trials, which evaluated cema-cel, their allogeneic CD19-targeting CAR T-cell therapy, in patients with relapsed/refractory large B cell lymphoma (r/r LBCL). Here’s what you need to know.

Allogene’s Allogeneic CAR-T Show Promise in Phase 1: A Breakdown

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Last week, the field of cancer immunotherapy reached a pretty exciting milestone with Allogene Therapeutics’ publication of Phase 1 results from their ALPHA/ALPHA2 trials, which evaluated cema-cel, their allogeneic CD19-targeting CAR T-cell therapy, in patients with relapsed/refractory large B cell lymphoma (r/r LBCL). Here’s what you need to know.

AbbVie and Xilio Partner Up to Advance Tumor-Activated T Cell Engagers

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This week, AbbVie made headlines by announcing a collaboration with Xilio Therapeutics to develop tumor-activated T cell engagers. The deal includes $52 million upfront and up to $2.1 billion in potential milestone payments. Let’s break down why this partnership is significant and how it might overcome long-standing challenges in solid tumor immunotherapy.

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